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In the pre-catalysis state, the S1 site would be occupied by the proximal SUMO2/3, a non-SUMO substrate protein, or by (acetyl-)CoA, as shown for ChlaDUB1 44
Using fluorescence emission spectroscopy (Varian Cary Eclipse Fluorescence Spectrophotometer, USA), it was found that pyocyanin displaces ethidium bromide (EtBr) bound to dsDNA
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In assessing early-stage PD, a consistent finding on brain MRI is reduced signal intensity and atrophy in the SN and putamen (213, 214)
