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Description
Among the seven conserved functional areas referred to as the Nrf2-ECH homology (Neh) domains of Nrf2, Neh1 primarily dimerises and attaches to small Maf (sMAF) proteins before going on to bind to DNA [13, 14]

Qu J, Sun M, Wang X, Song X, He H, Huan Y

This is particularly relevant given the shift toward nonoperative management of uncomplicated appendicitis

This makes it useful in the treatment and management of hemophthalmia
