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Its mechanism suggests potential benefit, but without validated dosing protocols or safety data in ischemic models, using it as a primary intervention introduces unquantified risk and reduces study reproducibility

doi:10.1016/j.regpep.2009.03.009 Yang D, Biragyn A, Hoover DM, Lubkowski J, Oppenheim JJ

Sundarraj, K., Raghunath, A
