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GHK-Cu also has strong topical relevance in peptide and cosmetic research, although published work notes that skin absorption can be limited without delivery support

Features that distinguish acneiform eruptions from acne vulgaris are: a positive time relationship between the introduction of the drug and the onset, a sudden and uncommon age of onset, pruritus, a monomorphic pattern and an involvement of seborrheic and extra-seborrheic areas such as the face, the neck, shoulders, arms, chest, and back [1,8]
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