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and Picardo M
In summary, increased ROS levels inhibit B cell function and promote the development of HCC
Table 4 specifies the composite biomarker panelspecies/flux, damage footprints, buffer status, iron/ferroptosis axis, signalling proxies and functional endpointsand codifies how those readouts trigger escalation, de-escalation and phase transitions
Consequently, this results in an upregulation of Bcl-2 mRNA expression, a downregulation of Bax mRNA expression, and a reduction in downstream inflammatory factors, ultimately leading to the inhibition of inflammation (122)
