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11 , eaau5758 (2019)

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Report that patients with elevated CRP levels benefit from statin therapy

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If patients are on a high-intensity statin, but not at the highest approved dose (i.e., on atorvastatin 40 mg or rosuvastatin 20 mg), increasing the dose further (i.e., to atorvastatin 80 mg or rosuvastatin 40 mg) is reasonable, but one should consider the minimal (6%) incremental LDL-C reduction with this uptitration as well as the dose-dependent nature of side effects of statins for patients at higher risk of such effects

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The extraction step employing a heptane-ethyl acetate mixture was repeated

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