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Therefore, in addition to prolactins potential influence on eating behaviors through leptin insensitivity, prolactin may further stimulate hyperphagia by decreasing dopaminergic tone ( Adipose tissue At physiologic levels (male 2-18 ng/mL, female 2-30 ng/mL), prolactin is important in maintaining adipogenesis and adipocyte differentiation
On other hand, arsenic-based compounds, with arsenic trioxide as the prototype, have already been approved by the FDA as a gold standard differentiation therapy to acute promyelocytic leukemia (APL) that is refractory to conventional therapies [133]
