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pylori infection chronic excess alcohol use pancreatic insufficiency intestinal bacterial overgrowth Gastrectomy/ bariatric surgery and gastritis Causes of food cobalamin malabsorption can be directly related with the stomach: Bariatric surgery it can depend on the type of procedure and what area of the stomach or intestines are removed Gastrectomy removal of part or all of the stomach Gastritis inflammation of the stomach lining Gastrectomy, bariatric surgery, and gastritis cause vitamin B12 deficiency due to an absence of stomach acids that help to remove vitamin B12 from food proteins, for example red meat

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Within the SELECT population with BMI 30 kg m 2 or 27 kg m 2 with at least one obesity-related comorbidity, the mean weight loss was 14.9% at week 68, compared with 2.4% with placebo 14

The health consequences of untreated B12 deficiency can be serious, including neurological damage and anaemia