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Factors influencing immunogenicity are categorized as: Extrinsic Factors: Aggregates, contaminants, or co-administered medications that trigger immune responses

However, trichloroacetic acid production in lysed human blood was significantly greater than production in rat blood and slightly higher than in mouse blood

Interestingly, the nuclear GSH pool appears to be dynamic and independent of cytosolic GSH, undergoing major shifts in relative concentration throughout the cell cycle which reaches upwards of four times the concentration found in the cytosol [76]