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The conclusion from this study is that SC administration was significantly more effective than oral administration of the same MTX dosage, according to the number of patients achieving ACR20 and ACR70 responses.

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Maternal vitamin B12 levels at approximately 18 weeks gestation is a reliable predictor of vitamin B12 status in lactation and in the infant through the first 6 months of life

But as mentioned, there's evidence to show that high oral doses of vitamin B12 can be just as effective at treating a deficiency
