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The reason is because peptides can have a short shelf-life

J Am Chem Soc (2014) 136:9798801

(68) highlighted in their review that pH-sensitive nanoparticles- commonly composed of materials such as alginate and chitosan- can modulate their size, solubility, and drug release rate in response to pH-dependent physicochemical changes

Both are highly effective, but they target different fitness goals