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The existing fetal niche has been implicated as a barrier to engraftment after it was documented that SCID recipients experienced successful engraftment of lymphoid specific cell lines and c-kit deficient mice underwent reconstitution of both erythroid and lymphoid cell lines after IUSCT (Fleischman and Mintz, 1979
Taken together, our work has detailed that FUS/TLS interacts with SMN and U1-snRNP (Fig
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