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This remodeling encompasses structural and functional adaptations, including synaptic LTP and depression, dendritic spine reorganization, neurogenesis, and alterations in networkwide oscillatory synchrony

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Upregulation of carbonyl reductase 1, an enzyme that protects cells against oxidative stress and cell death by inhibiting the formation of lipid peroxides, was observed in SFN-pretreated hepatic IRI mice in an Nrf2-dependent manner (Kwon et al., 2019)