deplete glutathione blood cells Application of depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy Glutathionyl Hemoglobin and Its Emerging
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Nutrients 14 , 2864 (2022)

The implications of NNMT inhibition extend far beyond simple cofactor availability, influencing fundamental cellular processes including mitochondrial biogenesis, oxidative stress management, and epigenetic regulation

The evidence is preliminary but promising
