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doi: 10.1681/ASN.2016010098 13

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[DOI] [PubMed] [Google Scholar] Cruzat V

Several small-molecule chaperones, such as amiloride [151], AT2101 (isofagomine) [152] and histone deacetylase inhibitors [153], have been shown to increase GCase activity and reduce oxidative stress in PD fibroblasts carrying GBA1 mutations or enhance GCase activity in GBA macrophage models