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Our understanding of the means by which GH and IGF-1 regulate growth was set into motion after experiments conducted in 1957 by Salmon and Daughaday showed that a factor in the serum (sulfation factor) was able to stimulate sulfate incorporation into cartilage in vitro [137]
Strengthening this system through lifestyle, precursor supplementation, and, where appropriate, modern delivery methods may not cure diabetes, but it offers a way to slow its progression, protect vulnerable organs, and reshape metabolic health for the long run
PloS One 10, e0143173
doi: 10.1038/s41586-021-03207-w 51 GangitanoE.TozziR.MarianiS.LenziA.GnessiL.LubranoC
