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Further, exogenous ketone bodies inhibit the proliferation of HCC cells and their invasiveness (Wang et al., 2019b)

On the other hand, it also decreases the oxidative stress, a cause of heart and blood vessels destruction

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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]
