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The boss has to win a bunch of battles

Increasing doses of levodopa were found to correlate with reduced levels of SCFA-producing bacteria (e.g., Lachnospiraceae ) and increased levels of Lactobacillus or Bifidobacterium , supporting the hypothesis that these alterations in the GM composition could be a consequence of PD medications, rather than of the disease itself [74]

Vitamin B12 injections are generally considered safe when administered by a qualified healthcare professional

The goal is matching risk tolerance to available options rather than seeking nonexistent perfect safety
