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Direct observation of methylmercury and auranofin binding to selenocysteine in thioredoxin reductase
Tissue atrophy of the CDN and DRG likely occurs due to the terminally differentiated, non-mitotic nature of neurons, which therefore are unable to survive prolonged damage downstream from the loss of FXN
We used 7-day-old mice randomly assigned to hypoxic or control groups
Most remarkably, ARA-290 initiated measurable regrowth of small nerve fibers in the cornea, providing direct evidence of nerve regeneration in humans
