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In CTS, patients might complain initially of tingling, numbness, or pain in the hand, sometimes irradiating to the shoulder, and worse at the end of the night or morning, right after waking up

Hypoxia, oxidative stress and inflammation

[DOI] [PMC free article] [PubMed] [Google Scholar] 177.Brines M., Grasso G., Fiordaliso F., Sfacteria A., Ghezzi P., Fratelli M., Latini R., Xie Q.W., Smart J., Su-Rick C.J., et al

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