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Overall, preclinical studies have shown that NAD + and mitochondrial metabolism play a crucial and intertwined role in aging and age-associated diseases, as well as being possible therapeutic targets for ameliorating these conditions

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However, in an online survey conducted between December 2021 and February 2023, 56.5% of the 470 respondents recruited through advertisements on websites related to AAS use reported PCT use when stopping AAS (Grant et al., 2023b)

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