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Description
Patients with Fitzpatrick IV-VI skin should be monitored for potential irritation during initial use, particularly in combination with other actives, and formulations should be pH-controlled (pH 3.5 or lower for efficacy without excessive irritation)

The authors acknowledge the National Cancer Institute, National Institutes of Health (P01CA229092) and the Jock and Bunny Adams Research and Education Endowment for support for this work

J.LochnerM.FrsterI.PowerC

doi: 10.1038/tp.2014.146
