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and one published human clinical study examining intra-articular injection in 12 patients with chronic knee pain, of whom 7 out of 12 reported relief lasting over 6 months [15]

Do not freeze it after reconstitution

Patients on Proton Pump Inhibitors or Metformin Long-term use of PPIs or metformin has been shown to impair B12 absorption

The proposed mechanisms range from well-validated (FDA-approved GLP-1 agonists for weight loss) to highly speculative (epitalon, thymosin alpha-1, MOTS-c) with limited or no human clinical validation
