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Curr Pediatr Rev

Autocrine VEGF signaling is required for vascular homeostasis
Further work needed to address whether these Hb multimers are implicated in the inflammatory microglia activation following IVH
Furthermore, A is able to promote the hyperphosphorlyation of Tau in both the cytosolic and synaptic compartments, which has been suggested as a potential explanation of the prion-like seeding hypothesis of Tau transmission inter-neuronally, accounting for the phosphorylated Tau detected in the CSF of AD patients (Wu et al., 2018