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Details are found in the "What It Does" section of the Turmeric and Curcumin Supplements Review (which includes our Top Picks among products)
[DOI] [PubMed] [Google Scholar] 5.Uebel CO, da Silva JB, Cantarelli D, et al

The critical transition point is the first needle puncture

From a mechanistic perspective, activation of the glucagon receptor stimulates hepatic lipid oxidation while limiting abnormal fat deposition in non-adipose tissues