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Description
Preclinical results have been promising, but high toxicity and low effectiveness in patients have limited use of these agents (Kaanders 2004)
Because of the loss of protective features and the damage they cause, chronic and neuropathic pain are viewed as disease states ( Although they often coexist and complicate each others outcome, the exact relation between chronic pain and depression has yet to be elucidated (Sheng et al., 2017)
L-Carnitine acts as a shuttle, transporting fatty acids to the mitochondria, where they undergo oxidation to produce energy
The epigenotype
