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Exposure to other environmental air pollutants, including short-term exposure to NO 2 , ozone, and carbon monoxide, as well as long-term exposure to NO x , PM2.5, and SO 2 , showed positive associations with hypertension, though without statistical significance [157]

Human-equivalent-dose extrapolation from that protocol lands around 650 mg/day for an 80 kg adult, but no human has been studied at any dose in a published trial

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If you have a medical condition or give blood on a regular basis, that number can climb rapidly
