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Several age-related factors cause this high prevalence: Atrophic gastritis (affects 8-9% of adults over 65) Decreased production of intrinsic factor Reduced stomach acid secretion Helicobacter pylori infection Medication interactions (especially with proton pump inhibitors) Untreated B12 deficiency can have serious effects on physical and neurological functions

Proc Natl Acad Sci USA 105: 1878218787 Yuneva MO, Fan TWM, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T, Mats JM, Alonso FJ, Wang C, Seo Y et al (2012) The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type

You may benefit from Kojic Acid in a water-based serum or cleanser