mitochondrial glutathione Unearthing the secrets of ROS and in bioenergetics: Trends in Biochemical Sciences Age-related loss of mitochondrial glutathione
Description
For instance, studies have discovered that certain anti-apoptotic genes are upregulated in HGSOC cells and are closely associated with chemotherapy resistance (156)
A specific type of TRx (f-type) has been shown to be glutathionylated on a cysteine residue away from its active site, resulting in a decreased activity towards specific target proteins including NADP-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [189]
Peptides are costly because they are complex to manufacture and must meet strict purity standards to be safe and effective
But the detoxification process isnt complete
