inhibition of glutathione reductase by Dinitrosyl-Iron-Dithiolate Complex Role of Glutathione in Cancer:

Lysosome and inflammatory defects in GBA1-mutant astrocytes are normalized by LRRK2 inhibition

NewportMTVanItallieTBKashiwayaYKingMTVeechRLA.New way to produce hyperketonemia: Use of ketone ester in a case of Alzheimers disease

Additionally, sirolimus treatment reduced fibrocyte concentration in IPF patients by 35%, showing potential for PI3K/mTOR inhibition in fibrosis management [148] (Table 2)

In addition, a foreign in vitro experimental study on human glioma A172 cells found that metformin increased the expression of AMPK/pAMPK/Bax protein and decreased the expression of mTOR/Bcl-2 protein in a dose and time-dependent manner, thereby inhibiting the proliferation and apoptosis of A172 cells