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Preadministration of high-dose alpha-tocopherol improved memory impairment and mitochondrial dysfunction induced by proteasome inhibition in rat hippocampus

As Sirt3 regulates mitochondrial antioxidative enzymes, a deficiency in Sirt3 can aggravate dopaminergic neuron degeneration (Outeiro et al., 2007

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& Nadeau, J
