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For those in a weaker state of health, it may be best to start with a smaller dose and increase over time
Citric acid also gets produced as a part of the energy metabolism in mitochondria
Additionally, SCFAs mediate bone mineralization and bone formation through the runt-related transcription factor (RUNX) signaling pathway, a key factor regulating the differentiation of osteoblast marker genes, which induces the directional differentiation of bone marrow stromal cells to bone and cartilage precursor cells (56)
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