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Description
IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms
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This is one of the theoretical advantages of the dual GIP/GLP-1 approach over the amylin/GLP-1 approach

Importance contested [edit] Despite experimental findings that suggest a role for dendritic spine dynamics in mediating learning and memory, the degree of structural plasticity's importance remains debatable
