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Although HLA-DR2 has been identified as a major genetic risk factor for MS its direct association with Cbl deficiency remains uncertain

Furthermore, in rats that are subjected to cecum ligation and puncture (CLP) induced-AKI, early glomerular syndecan-1 loss is followed by the loss of hyaluronic acid 7 h after CLP is initiated, and this is accompanied by alterations in glomerular sialic acids and the molecular composition of the glomerular filtration barrier (95)

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Clinicians using epitalon rely on extrapolation from animal data and observational reporting not clinical trial dose-finding