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NF-B activation has been reviewed in the inhibition of apoptosis, and induction of tumorigenic enhancing genes such as MMP-9, Bcl-xl, XIAP, and cyclin D1, leading to metastasis (Fuchs, 2013)
thus, experimental interventions carrying significant systemic risks face stringent safety barriers before entering earlyphase human trials
2024 Apr 14];17(2):187
Treatment with MSCs may affect the differentiation and maturation of DCs, resulting in the suppression of IL-12 (213)
