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These include serious infection, uremia or renal failure, drugs with bone marrow suppression properties (e.g., chloramphenicol), or concurrent undiagnosed folic acid or iron deficiency anemia

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. Doctors may not be prescribing oral vitamin B12 formulations because they may be unaware of this option or have concerns regarding its effectiveness Objectives: To assess the effects of oral vitamin B 12 versus intramuscular vitamin B 12 for vitamin B 12 deficiency. Selection criteria: Randomized controlled trials (RCTs) comparing the effect of oral versus IM vitamin B 12 for vitamin B 12 deficiency

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Vitamin B12 is essential for nerve function, red blood cell production, and DNA synthesis

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