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[DOI] [PubMed] [Google Scholar] 44.Vider J, Laaksonen DE, Kilk A, Atalay M, Lehtmaa J, Zilmer M, Sen CK

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD

KB serve as an efficient mitochondrial fuel, where it can alter the NAD+/NADH and Q/QH2 couples and reduce production of mitochondrial ROS

505507 ARIs Epalrestat is an aldose reductase inhibitor that prevents the accumulation of sorbitol and fructose within nerve cells, which can cause osmotic stress and neuronal damage