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For the Mitostress test, oxygen consumption rate was measured first without any supplementation (basal respiration), then cells were treated subsequently with 1 M oligomycin A (ATP-dependent respiration), 0.75 M FCCP (spare respiratory capacity), and a mixture of 1 M rotenone and 1 M antimycin A (non-mitochondrial oxygen consumption)

doi:10.1016/j.devcel.2004.06.001

Promising results were also seen when this antibody was added to BEAM conditioning prior to auto-HCT in phase I trials of patients with relapsed B-NHL, T-NHL, or HL

In addition, autophagy appears to have a crucial role in dampening the immune response after irradiation as depletion of key autophagy regulators ATG5 or ATG7, thereby blocking mitophagy, increased cytosolic mtDNA after radiotherapy [110]