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Other studies showed that the incubation of rat liver mitochondria with butyl-malonate (a dicarboxylate carrier inhibitor) and phenyl-succinate (a 2-oxoglutarate carrier inhibitor) inhibits GSH transport across IMM

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Avoid repeated freeze-thaw cycles, which can promote disulfide rearrangement and loss of the cyclic structure

The first is the result of a mechanical blockade occurring in the biliary duct system caused by the presence of a gallstone, or a consequence of a pressure on bile ducts caused by tumor mass, bile duct tumors themselves, pancreatic tumors, pancreatitis, cysts, or primary sclerosing cholangitis