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The mechanistic target of rapamycin pathway downregulates bone morphogenetic protein signaling to promote oligodendrocyte differentiation

The combination of these two sources of inflammation could make you more likely to experience ear damage compared to people who have a less active IL6 gene

This triggers g-protein coupled activation of calcium-inhibitable adenylyl cyclase 6 (AC-VI) and inhibition of calcium/calmodulin-dependent phosphodiesterase (PDE), causing enhanced accumulation of cyclic AMP (cAMP) and activation of protein kinase A (PKA) [81]
