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For instance, vitamin B12 supplements can interact with gastric acid inhibitors or metformin, and B6 can interact with certain antibiotics and epilepsy medications
Nat Rev Endocrinol (2010) 6(7):38095

Activation of the PI3K-Akt pathway promotes neuroprotection of the -opioid receptor agonist against cerebral ischemia-reperfusion injury in rat models
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