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For 2 days preceding each infusion, subjects consumed a standard diet providing approximately 2500 kcal/d with protein content of 1 g/kg/d to prevent negative energy balance (Figure 1)

Catalases specificity for hydrogen peroxide might limit its efficacy under conditions where other reactive oxygen species contribute to oxidative stress, requiring broader targeting strategies

This paper describes that treatment of human cancer cells having steroid hormone receptors with the appropriate hormone, oestrogen and/or progesterone, significantly increases the potency of cisplatin and its analogue carboplatin by causing the overexpression of HMGB1

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