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However, studies have not been able to establish a link between vitamin B12 supplementation and a lower risk of heart disease

The article establishes two cumulative caps across an aggregated code set covering 62320, 62321, 62322, 62323, 62324, 62325, 62326, 62327, 64479, 64480, 64483, and 64484: no more than 3 epidural injection sessions (6 injections) may be reported in any rolling 6-month period, and no more than 6 sessions (12 injections) may be reported in any rolling 12-month period

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Another proposed mechanism involves the binding of homocysteine to the collagenous matrix of bone, which may modify collagen properties and reduce bone strength (reviewed in 113)