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Clinical Orthopaedics and Related Research, 451, 7884

Per the Costco product page, Kirkland Signature Energy Shots come in a pack featuring 48 bottles and retailing for $39.99 online

While the study reported positive effects on cerebrospinal fluid biomarkers of neuroinflammation and neurodegeneration, it did not meet its primary clinical efficacy endpoint, highlighting the difficulty of translating biological signals into measurable clinical benefits in a heterogeneous patient population (65)

Sharma et al., 2022)
