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Description
As the central enzyme of the endogenous lipogenesis pathway, fatty acid synthase (FAS) is directly involved in regulating lipid deposition, making it a critical marker for assessing dietary effects (Schroeder et al., 2021)
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In vitro and ex vivo uptake of glutathione (GSH) across the intestinal epithelium and fate of oral GSH after in vivo supplementation
Disruptions in this axis can lead to increased susceptibility to ferroptosis, highlighting the importance of considering the holistic hepatic environment in disease pathogenesis
