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Recent studies have also shown that the microbial products and/or alterations in the composition of the gut microbiota give rise to marked changes in neuronal activity and the composition of neuronal subsets in the ENS (198, 200204, 211, 214, 243, 244, 337)

These effects were achieved by different routes of application including intragastric and local application

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Its research profile makes it especially relevant in models focused on body-composition pathways, metabolic adaptation, food-intake signaling, satiety-related biology, and next-generation incretin-adjacent research