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Description
Knockdown of nitric oxide synthases (NOS) will decrease the NO concentration which sensitized cell to ferroptosis [54, 55]
This extends half-life from minutes to ~165 hours, allowing weekly administration in research
Within the brain the principal functions of nNOS produced NO are in the mediation of long-term synaptic transmission

CD44 is expressed on leukocytes and has a role in mediating the innate immune response
