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When ovarian cancer cells were treated with NAC prior to Dox treatment, it enhanced ATM and p53 phosphorylation, potentiating the effect of Dox on ovarian cancer cells [28]

32 This is due to metabolic reprogramming in the BM niche, which shifts from oxidative phosphorylation to aerobic glycolysis reducing ATP and simultaneously increasing NAD +

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[DOI] [PubMed] [Google Scholar] 38.Loria C.M., Klag M.J., Caulfield L.E., Whelton P.K
