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9, A, fluorescently labeled free-DNAzymes could rarely appear inside the brain in a diffuse pattern within the brain parenchyma for up to 4 and 24 h, indicating that DNZ-NLP passes the BBB but at a lower rate

Low GSH levels associate with metabolic syndrome, cardiovascular disease, chronic kidney disease, NAFLD/NASH, Parkinsons disease, Alzheimers disease, autoimmune conditions, HIV infection, and cancer

Despite the availability of pharmacological, non-pharmacological, and surgical treatments, including brain, spinal, and vagus nerve stimulators, patients continue to experience progressive weakness, and no treatment has yet succeeded as a true disease modifier [13]

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