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- and -chains of fibrin, factor V, 2 -antiplasmin ( 2 -AP), thrombin-activable fibrinolysis inhibitor, plasminogen, and plasminogen activator inhibitor-2 have also been reported as substrates for FXIIIa [4,5,6]

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268 Reaction conditions, including temperature, pressure, solvent, and catalyst, significantly influence the rate, selectivity, and product quality in drug synthesis reactions